Bicarbonate buffered ultrafiltration leads to a physiologic priming solution in pediatric cardiac surgery

Modified ultrafiltration after cardiopulmonary bypass in pediatric cardiac surgery.

BACKGROUND Cardiopulmonary bypass in children results in considerable water retention, especially in neonates and small infants. Dilution of plasma proteins increases water loss into the extravascular compartments. Excessive total body water may prolong ventilatory support and may contribute to a prolongation of intensive care convalescence. After discontinuation of cardiopulmonary bypass, modi...

Ultrafiltration in Cardiac Surgery

____________ _ Cardiopulmonary bypass (CPB) may result in hemodilution and volume overload. Restoration of a normal hematocrit is important for post-operative myocardial performance. Diuretics, conventionally used in the post-operative period may be ineffective due to renal impairment or lead to electrolyte imbalance. Hollow-fiber hemofilters, made of an anisotropic polysulfone membrane (AMICON...

Effect of priming solution and ultrafiltration on post-operative bleeding and blood transfusion in cardiac surgery. Randomized controlled trial

[Effect of priming solution and ultrafiltration on post-operative bleeding and blood transfusion in cardiac surgery. Randomized controlled trial].

OBJECTIVE Assess the effectiveness of priming the extracorporeal circulation system with albumin-mannitol combined with ultrafiltration during extracorporeal circulation to reduce post-operative bleeding and transfusion requirements in heart surgery, as well as its impact on the fluid balance, coagulation and hematocrit parameters, re-operation for bleeding, ICU, and hospital length of stay. ...

In vitro biocompatibility evaluation of a novel bicarbonate-buffered amino-acid solution for peritoneal dialysis.

BACKGROUND Conventional lactate-buffered peritoneal dialysis fluids containing glucose as the osmotic agent have been shown to compromise important peritoneal host defence functions. The current study employed an in vitro model using activated peripheral blood mononuclear leukocytes (PBMC) for the preclinical biocompatibility assessment of a novel bicarbonate-buffered peritoneal dialysis fluid ...